According to the World University Rankings 2020-2021, UoN has been ranked 6.8% globally out of twenty thousand universities. This year, University of Nairobi ranks as follows: Quality of Education, Alumni Employment and Quality of faculty have an Overall Score of 68.4 with a a research performance rank of 1294 , with a world rank of 1357,and leading in Kenya. The rankings are unique in that: Objective indicators are used for all four key pillars underlying the methodology of the ranking (quality of education, alumni employment, quality of faculty, and research performance) with no reliance on surveys and university data submissions.

The Center for World University Rankings (CWUR) is a leading consulting organization providing policy advice, strategic insights, and consulting services to governments and universities to improve educational and research outcomes. Since 2012, CWUR has been publishing the only academic ranking of global universities that assesses the quality of education, alumni employment, research output, and citations without relying on surveys and university data submissions.